An outstanding servant to the club, Stapley debuted as a teenager and has 20 tries to his name ahead of his final outing.
Virtual ever-present this term, Harry Stone, joins him in the engine room.
The 21-year-old has missed just one fixture and has crossed the whitewash six times.
And as the season ends, another milestone sees tight-head prop Ryan Lomas reach 50 appearances against Tigers.
The Irishman is one of two changes to the pack, with Max Marshall set for a first start at hooker.
Paddy Harris completes the front row.
The back row is also unchanged, captain Willo Bicknell joined by flankers Fergus Dick and Aaron Tull for the fifth consecutive game.
Cooke comes back in at No. 10
Ed Hoadley is at scrum-half but there is a change outside him, Mike Cooke back in the No. 10 role.
The leading point-scorer’s late conversion against Rosslyn Park loss left him on 137 for the season.
Twelve-try Morgan MacRae is at inside centre, again partnered in midfield by fellow Welshman Ellis Jones.
With Lamb switching to full-back, Zach Clow – second top try-scorer with 14 this term – moves back to the right wing.
And the starting line-up is completed by Swedish international Axel Kalling-Smith, the left wing looking to up his haul from 13.
Breese and Grundy back on the bench
George Breese returns to the squad as one of two props ready to make an impact, the other James Baker eyeing up a 461st appearance.
He moved past Tigers coach Matt Riley (458) as the record-breaking one-club man in the Anglo-French semi-professional era last month.
Rams opt for a 3-2 bench split with teenage lock Paddy Jackson the other forward.
Rowan Grundy has recovered from the split lip he suffered at Rotherham Titans to take a slot among the replacements.
And fresh from playing at Northampton Saints’ Franklins Gardens last Saturday, Royal Air Force scrum-half Sam Boxhall rounds out the matchday 20.
Harrys Bicknell (hooker) and Judd (back row) are travelling reserves alongside fly-half James Gilman.
Rams Team v Sedgley Park
(15-9, 1-8) Lamb, Clow, Jones, MacRae, Kalling-Smith, Cooke, Hoadley; Harris, Marshall, Baker, Stapley, Stone, Dick, Tull, W Bicknell ©
Replacements: Breese, Baker, Jackson, Grundy, Boxhall
Travelling Reserves: H Bicknell, Judd, Gilman
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